欢迎来到肽谷生物-专业多肽定制。

服务热线:+86-(0)-18115476705

196P01

Prion Protein (106-126) (human) trifluoroacetate salt

H-Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly-OH trifluoroacetate salt

纯度:>95%HPLC
储存条价:-20 ± 5 °C,避光,干燥。

另提供从粗品至98%纯度规格,具体请联系我们!
本产品仅用于科学研究,不得用于人体!


产品详情

Cat#:196P01
序列(三字母):H-Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly-OH trifluoroacetate salt
序列(单字母):KTNMKHMAGAAAAGAVVGGLG
类似名:Prion Protein Fragment (106-126), human
分子式:C₈₀H₁₃₈N₂₆O₂₄S₂
分子量:1912.27
CAS#:148439-49-0
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Apoptosis & Necrosis
描述:An altered form of the large cellular prion protein accumulates in the CNS of patients with neurodegenerative disorders, and its protease-resistant core aggregates extracellularly into amyloid fibrils. This process is accompanied by nerve cell loss. The 21-peptide KTNMKHMAGAAAAGAVVGGLG is used as a model to investigate neurodegeneration in prion diseases. Prion Protein (106-126) forms fibrils in vitro and causes apoptotic cell death in neuron culture. Its neurotoxicity depends on the presence of microglia and is induced by microglia. It could be demonstrated that KTNMKHMAGAAAAGAVVGGLG is able to bind to DNA, a circumstance which led to the assumption that the integral protein could also bind to DNA under appropriate solution conditions.


订购流程:

1)通过电话(+86-(0)-18115476705)邮件(sales@tgpeptide.com)联系我们;
2)提供合成多肽的具体需求,包括序列、质量和纯度,技术部门评估后给与报价。
3)签订多肽合成合同,交付合成预付款,科研机构先使用再付款!
4)合成过程定期跟您汇报合成进度及情况;
5)根据合同内容,随货提供发票;
6)如因本公司原因不能交货或合成失败,退还所有合成款!

Copyright ©2020 南京肽谷生物科技有限公司 备案号:苏ICP备19062824号-1 网站地图