Cat#：140P222
序列（三字母）：Pyr-Arg-Thr-Lys-Arg-AMC trifluoroacetate salt
序列（单字母）：Pyr-RTKR-AMC
分子式：C₃₇H₅₇N₁₃O₉
分子量：827.94
CAS#：155575-02-3
合成方法：Synthetic
存储条件：-20 ± 5 °C
描述：The fluorogenic substrate pERTKR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 2·10⁴ M-¹s-¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Also cleaved by proprotein convertase 4. Pyr-RTKR-AMC is an excellent substrate for flavivirin.