Cat#: 108P03
序列（三字母）：H-Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile-OH (Disulfide bond)
序列（单字母）：ECLWMDWVTEKNINGHQAKFFACI
类似名：Metalloproteinase Inhibitor 2 (145-168) (human, bovine), CSC-21K (145-168) (human, bovine), Tissue Inhibitor Of Metalloproteinases-2 (145-168) (human, bovine)
分子式：C₁₃₁H₁₈₉N₃₃O₃₅S₃
分子量：2882.34
CAS#：1872435-10-3
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Angiogenesis
描述：TIMP-2 (145-168) (human, bovine) corresponding to loop 6 of tissue inhibitor of metalloproteinase-2 (TIMP-2) is a potent inhibitor of angiogenesis. It displayed a metalloproteinase (MMP)-independent anti-angiogenic activity which could be separated from the MMP-dependent activity of TIMP-2. In contrast to the MMP-dependent activity which only inhibited embryonic neovascularization it was able to inhibit both embryonic and mitogen-stimulated angiogenesis in vivo.