Cat#: 107P107
序列（三字母）：H-Arg-Asp-Leu-Pro-Phe-Phe-Pro-Val-Pro-Ile-Asp-OH
序列（单字母）：RDLPFFPVPID
类似名：iAβ11
分子式：C₆₄H₉₄N₁₄O₁₆
分子量：1315.54
CAS#：182912-63-6
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Alzheimer´s Disease
描述：The undecapeptide RDLPFFPVPID (iAβ11) has a similar degree of hydrophobicity as the native amyloid β-peptide (Aβ), but with a low propensity to adopt a β-sheet conformation. It is therefore called anti-β-sheet peptide or β-sheet inhibitor. iAβ11 binds to Aβ, inhibits Aβ fibril formation and partially disaggregates preformed fibrils in vitro. This anti-β-sheet peptide may serve as a starting point to design inhibitors of amyloidogenesis in vivo.