产品详情
Cat#: 107P100
序列(三字母):H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH
序列(单字母):YEVHHQKLVFF
类似名:β-Amyloid (10-20)
分子式:C₇₁H₉₉N₁₇O₁₆
分子量:1446.67
CAS#:152286-31-2
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Alzheimer´s Disease
描述:The amyloid precursor protein (APP) is cleaved within the amyloid β-protein region by a putative APP secretase to release its extracellular portion. Gelatinase A, the matrix metalloproteinase MMP-2, possesses such APP secretase-like activity, effectively hydrolyzing also the 固相合成 amyloid β-protein fragment (10-20) YEVHHQKLVFF at the normal processing site, the Lys¹⁶-Leu¹⁷ bond (Km approx. 0.13 mM).
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