产品详情
Cat#: 107P25
序列(三字母):H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH
序列(单字母):DAEFRHDSGYEVHHQK
类似名:β-Amyloid (1-16), human
分子式:C₈₄H₁₁₉N₂₇O₂₈
分子量:1955.03
CAS#:131580-10-4
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Alzheimer´s Disease
描述:The Cu²⁺ complex of this soluble amyloid β-protein fragment showed significant oxidative activities toward the catechol-like substrate 1,2,3-trihydroxylbenzene (pyrogallol) and plasmid DNA cleavage.
The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.
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