Cat#: 107P23
序列（三字母）：H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-OH
序列（单字母）：DAEFRHDSGYEVHH
分子式：C₇₃H₉₉N₂₃O₂₅
分子量：1698.73
CAS#：186319-74-4
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Alzheimer´s Disease
描述：The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β- followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged.