Cat#：211P15
序列（三字母）：Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH (Disulfide bonds between Cys⁷ and Cys²⁸/Cys¹³ and Cys³³/Cys¹⁷ and Cys³⁵)
序列（单字母）：pEFTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
分子式：C₁₇₉H₂₇₄N₅₀O₅₅S₇
分子量：4230.91
CAS#：129203-60-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Ion Channel Modulating Agents
描述：Iberiotoxin (IbTx), from the venom of the scorpion Buthus tamulus, shows 68% sequence homology with charybdotoxin, another scorpion-derived peptidyl toxin. Although these two toxins both inhibit the high conductance Ca²⁺ activated K⁺ channel, they appear to bind at different sites on the channel and modulate channel activity by different mechanisms. Thus, iberiotoxin can be used to selectively study the function of the high conductance Ca²⁺ activated K⁺ channel.