产品详情
Cat#:207P06
序列(三字母):H-D-Arg-Pro-Lys-Pro-D-Trp-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH₂
序列(单字母):rPKPwQwFwLL-NH₂
类似名:[DArg1, DTrp5,7,9, Leu11] Substance P
分子式:C₈₁H₁₁₀N₂₀O₁₂
分子量:1555.89
CAS#:122481-75-8
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Cancer Research
描述:This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
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