Cat#：137P24
序列（三字母）：Ac-D-Trp-Leu-Asp-Ile-Ile-Trp-OH
序列（单字母）：Ac-wLDIIW
类似名：Ac-[DTrp16] Endothelin-1 (16-21), human
分子式：C₄₆H₆₂N₈O₁₀
分子量：887.05
CAS#：143037-33-6
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cardiovascular System & Diseases
描述：Displays high affinity for the ET-A receptor (IC₅₀ = 0.13 µM) and inhibits the ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells. The hexapeptide binds specifically to the pituitary GnRH receptor exhibiting agonistic activity.