Cat#：211P29
序列（三字母）：H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH₂ (Disulfide bonds between Cys³ and Cys¹⁴/Cys⁵ and Cys¹⁸)
序列（单字母）：ALCNCNRIIIPHMCWKKCGKK-NH₂
分子式：C₁₀₆H₁₇₆N₃₄O₂₃S₅
分子量：2455.11
CAS#：58694-52-3
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Ion Channel Modulating Agents
描述：Tertiapin (TPN), a potent inhibitor of the inward-rectifier K⁺ channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin will be a powerful ligand for purifying functional channels as well as for screening pharmaceutical agents against these channels.