Cat#：166P07
序列（三字母）：H-Phe-Glu-Trp-Thr-Pro-Gly-Tyr-Trp-Gln-Pro-Tyr-Ala-Leu-Pro-Leu-OH
序列（单字母）：FEWTPGYWQPYALPL
类似名：AF11377
分子式：C₉₅H₁₂₂N₁₈O₂₂
分子量：1868.12
CAS#：171492-13-0
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cytokines/Chemokines & their Receptors
描述：AF11377, FEWTPGYWQPYALPL, blocked IL-1α-binding to the type I IL-1 receptor with IC₅₀ = 1.9 nM. AF11377 blocked IL-1-driven responses in human and monkey cells. This is the first example of a high affinity peptide that binds to a cytokine receptor and acts as a cytokine antagonist.