Cat#：141P16
序列（三字母）：H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ acetate salt
序列（单字母）：DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH₂
分子式：C₁₄₉H₂₃₄N₄₀O₄₇S
分子量：3369.8
CAS#：133514-43-9
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Diabetes
描述：Exendin (9-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. It has also been described as an antagonist of the putative exendin receptor. Exendin (9-39) blocks the stimulatory action of GLP-1 (7- 36) amide and of exendin-4 on cAMP production in pancreatic acini. Moreover, exendin (9-39) was shown to be safely used to abolish the incretin effect of GLP-1 without interfering with the control of insulin secretion by circulating nutrients.